MIBG Therapy

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Used for tumors that take up MIBG such as neuroblastoma, the treatment is intravenously injected over the course of two hours, which is made up of MIBG, which functions as a carrier that delivers I131 to tumor cells as to discharge sufficient radiation exterminating the target cells. For this treatment you should be admitted to a hospital for at least 3 days, below are a set of instructions to follow:
  • Fasting from solid food for at least 2 hours before and two hours after treatment is required.
  • The following medications should be withheld for 5 days at least:
    1. Tricyclic antidepressants
    2. Antihypertensives
    3. Sympathomimetics
    4. Decongestants containing pseudoephedrine, phenylpropanolamine and phenylephrine
  • Before and after the treatment Lugol’s solution should be administered as instructed.
  • As a baseline both a CBC and a KFT (Kidney Function Test) should be provided.
  • An anti-emetic should be administered the same day the treatment was administered to be carried on over the course of 3 days.
  • The radiopharmaceutical will be intravenously injected over two hours.
  • Fluid intake increase and frequent urination are requested.